Use the links in the box on the left for information on each of the studies being conducted by PASA.
The exact number and type of studies to be conducted will depend on the quantity and quality of applications received and if the optional funding is provided. The types of studies correspond to PASA's three Aims.
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Type of Study
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Population
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Focus
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Goal
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Aim 1
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Discovery Studies
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Animal Models
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Alcohol Dependence
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Screen potential compounds for therapeutic potential in animal models for ASUD and PTSD
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Aim 2
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Human Proof of Concept Studies
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Human Subjects
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Compounds from discovery studies or similar preclinical testing
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Take the best candidate compounds from discovery to test for medical safety and for indicators of potential effectiveness
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Aim 3
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Phase II Safety and Preliminary Efficacy Clinical Trials
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Human Subjects
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Potential medication combinations in patients with ASUD and concurrent PTSD with or without the chronic effects of mild TBI
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Identify potential medications or medication combinations for ASUD with PTSD;
Determine if there is enough evidence of efficacy to support moving forward with Phase III clinical trials
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